SAMSON Web is live: create, predict, render, and share molecular systems directly in your browser! Today, we are incredibly proud to introduce SAMSON Web: a browser-based molecular design environment. No installation. No plugin. No account required. Open SAMSON Web, create or import a molecular system, work on it directly in the browser, and share it. Not a screenshot. Not a video. A real interactive 3D molecular document. With the full context. With SAMSON Web, you can start in many ways: • open molecular files from your device • import and export common formats such as PDB, MOL2, and more • fetch structures from databases • predict structures (currently with AlphaFold 2, Boltz-2, and Chai-1x) • build from atoms, fragments, and assets • import cloud job results And once your system is in the browser, you can work on it: select, measure, prepare, align, minimize, annotate, edit, create a new version, and share again. Because one of the most important parts of SAMSON Web is sharing interactive documents. Scientific communication still relies too much on molecular images or movies. But molecular systems are three-dimensional. And they have context, annotations, associated data, versions, and intent. With SAMSON Web, you can share an interactive molecular document that preserves context in seconds. A collaborator, student, reviewer, customer, or colleague can open it in the browser, rotate it, zoom in, inspect annotations, associated logs and data, understand the model directly, and even edit their own copy. Remote collaborators, even during a Zoom or Teams session, can now explore designs as they want, edit, and send you back their changes. SAMSON Web also helps you create high-quality visuals directly in the browser: • advanced rendering effects • custom backgrounds • 3D skyboxes • path tracing • advanced materials • snapshots and render-ready scenes Modern molecular design produces much more than coordinates: prediction results, alignments, tables, metadata, trajectories, reports, annotations, and intermediate files. SAMSON documents preserve it all, and SAMSON Web also includes a Data Explorer to explore and edit rich scientific data next to molecular structures. The goal is to make molecular documents richer and more useful: scientific workspaces where structure, data, calculations, and interpretation live together. You start locally by default (files you open stay on your device unless you choose to share them or use cloud features). You do not need an account to create and share. Creating an account unlocks versioned documents and history, permission controls, and access to your data from anywhere. SAMSON Web is live. You can start in seconds. The link is in the first comment. #OneAngstrom #SAMSON #MolecularDesign #ComputationalBiology #DrugDiscovery #ProteinDesign #StructuralBiology #MaterialsScience #Nanoscience #AlphaFold #Boltz #Chai #MolecularVisualization #ScientificComputing #AIForScience

On April 30, I’ll be hosting a webinar to introduce SAMSON 2026 - the new release of our platform for molecular modeling and simulation. This version brings major improvements across SAMSON, including new tools to help researchers move faster from structure to insight. During the webinar, I’ll show in particular how to: ✅ use the new Path Analyzer to analyze paths and molecular dynamics trajectories and generate advanced plots in just a few clicks ✅ use UMA Force Fields in interactive simulations ✅ use the new Strain Explorer to analyze ligand poses If you work in molecular design, computational chemistry, structural biology, materials science, or related fields, this session will give you a concrete look at what’s new and how it can accelerate your workflows. 📅 April 30, 2026 🕔 5 PM CET / 11 AM EST / 8 AM PST Register here: oneangstrom.com/webinar-intr… If you’d like to follow along during the webinar, you can create a free account on SAMSON Connect and install SAMSON beforehand. Excited to share what we’ve been building! #SAMSON #MolecularDesign #ComputationalChemistry #DrugDiscovery #MaterialsScience #MolecularModeling #LifeSciences #Simulation #Chemoinformatics #OneAngstrom

Big update from OneAngstrom: SAMSON 2026 R1 is here! This release brings powerful new capabilities: the Path Analyzer, the Strain Explorer, and integration of Meta’s UMA force fields - plus more improvements across the platform. We’re excited to keep pushing SAMSON forward for the molecular modeling community! Learn more: • What’s new in SAMSON 2026 R1: documentation.samson-connect… • Path Analyzer: samson-connect.net/extension… • Strain Explorer: samson-connect.net/extension… • UMA force fields: samson-connect.net/extension… #MolecularDesign #ComputationalChemistry #MolecularModeling #SAMSON #MaterialsScience #DrugDiscovery

The OneAngstrom spin out has been building some of this in @SAMSONConnect. This space is still very immature and the other SaaS players like OpenBio, Rowan, Tamarind, etc. will scratch at the itch until the winners emerge. I would love to have workflows entirely in MOE with all the latest methods. This is of course possible already through SVL but that negates the whole issue of “writing more glue”. Let’s hope the new French entry kicks those master Canucks into gear over at CCG. They already have the best “Molecular Operating Environment”.

OneAngstrom (@AngstromOne) is at the Drug Discovery Chemistry Europe conference in Barcelona. If you are there as well and want to meet and discuss how the @SAMSONConnect molecular design platform can help you with your computational projects, just let us know. #DDCEurope

Excited to announce the general availability of Chai-1 in SAMSON! Like AlphaFold 3, Chai-1 is a state-of-the-art foundation model for biomolecular structure prediction which handles proteins, small molecules, DNA, RNA, glycosylations, etc. One particularly exciting feature is the possibility to specify contact and pocket restraints! Congratulations to the Chai-1 team at @chaidiscovery ! #chai1 #samson #OneAngstrom

PhD opening! As a member of the PhotoCaM Marie Skłodowska-Curie Actions Doctoral Network, OneAngstrom is seeking a highly motivated individual with a strong background in computer science for a fully funded PhD Position. Key Responsibilities Develop and implement innovative computational methods for accurate pKa prediction. Collaborate with our European partners, contributing to a rich, international research environment. Prerequisites – Master’s degree in computer science or a related field. – Demonstrated expertise in computational methods, algorithms, and programming. – Strong analytical and problem-solving skills. – Excellent communication and teamwork abilities. Unique Opportunity Be a part of an EU-funded international network, gaining unparalleled exposure. Travel across Europe to collaborate with our network partners, enriching your research experience and cultural understanding. If you have a strong computational background and a drive to innovate, we would love to hear from you! 📩 How to apply: Send a mail to photocam-phd@oneangstrom.com Learn more at 1-a.io/phd.

We recently introduced SAMSON 2024 in a webinar. If you missed it, or would like to watch it again (or simply share it), here's the direct link to the video: youtube.com/watch?v=9fWndkgP… The video is filled with tips about AI, modeling, visualization, Python development, collaboration tools, and more: 00:00 OneAngstrom and SAMSON 03:16 SAMSON's top six distinctive features 06:55 Documentation and interactive tutorials 09:00 Getting answers and getting things done with SAMSON AI 13:15 Selecting with the Document View and the Context Toolbar 16:29 Selecting with the Viewport and Selection filters 17:37 Selecting with Selection Commands 18:35 Selecting with the Node Specification Language and SAMSON AI 21:26 Selecting with the new Interactive Sequence Viewer 23:47 Producing studio-quality renderings with Cycles, the integrated path tracer from Blender 26:32 Creating new visualizations quickly with the new Visual Preset Editor 31:52 Creating movies with the Animator 33:39 Using the new Cloud Job Manager and predicting protein structures 36:40 Importing and visualization GROMACS simulations 39:39 Creating apps and executable documents with the integrated Python Environment 43:17 Publishing documents securely and privately on SAMSON Connect 45:48 Creating and publishing your social profile on SAMSON Connect 46:26 Creating groups and organizing teams on SAMSON Connect 47:20 Sharing documents with users and groups 50:00 Beginning Q&A 51:10 Using Martinize to create coarse-grained structures 55:35 Importing and sharing cloud jobs 58:07 Contacting the developers We hope you'll find it valuable!

🎉 Introducing the SAMSON Academic Site License! We are excited to announce the launch of the SAMSON Academic Site License — a new initiative designed to empower universities and research institutions with unlimited access to SAMSON and over 90 extensions. At OneAngstrom, we believe in the power of education and research to drive innovation and solve the world’s most pressing challenges. The SAMSON Academic Site License is a significant step forward in our commitment to supporting the global scientific community. Key Benefits of the SAMSON Academic Site License 🔬 Unlimited Access: All faculty, researchers, and students in your group, department or entire institution enjoy unlimited access to SAMSON and over 90 extensions, enabling seamless integration into coursework, research projects, and collaborative efforts. 💼 Automatic licensing: With the Academic Site License, everyone with your email domain automatically gains full access to the entire package. Say goodbye to time-consuming user management. 🌐 For everyone, at the same time: With the Academic Site License, every user has unlimited access to SAMSON and all included extensions, anytime, without restrictions. No more tracking tokens or managing user access — enjoy seamless usage without the hassle. 📈 Training included: With the Academic Site License, all group leaders and faculty members receive complimentary onboarding sessions to quickly master SAMSON. From AI, construction and simulation to analysis, rendering, animation, scripting, and preparing executable SAMSON documents for lectures and research tasks — SAMSON will soon hold no secrets for you. 💎 Maximize value, minimize cost: The Academic Site License is the most cost-effective way to unlock the full power of SAMSON, providing unlimited access to all Professional features and over 90 extensions. Empower your institution with cutting-edge capabilities while staying within budget. Why Choose SAMSON? SAMSON is trusted by leading researchers and institutions around the world for its versatility, advanced features, and user-friendly interface. Join the SAMSON Community Today! Be part of a growing network of academic institutions, biotechs and pharmas that are using SAMSON to enhance education, accelerate research, and drive innovation. With the Academic Site License, your institution can provide the next generation of scientists and engineers with the tools they need to succeed. We look forward to welcoming your institution to the SAMSON community! Learn more with the link in the next tweet! 🔗

Upcoming webinar by NVIDIA and OneAngstrom! (please share!) Pharmaceutical researchers are continually on the quest for better, faster ways to design drugs, but juggling independently designed software and data sources has created a long-standing challenge. NVIDIA and OneAngstrom are collaborating to reduce this fragmentation. Join the discussion and see how molecular design is made more accessible than ever before by accessing powerful, state-of-the-art generative AI services through the SAMSON molecular design platform. Date: Thursday, February 15, 2024 Time: 10:00 –11:00 a.m. PT Duration: 1 hour In this webinar you will learn: - How integrative molecular modeling results in streamlined, state-of-the-art workflows for scientists - To access NVIDIA BioNeMo™ in just a few clicks to predict protein structures and dock entire libraries of ligands - To combine BioNeMo with all other extensions available in SAMSON for modeling, simulation, analysis, visualization, scripting, and more Register at info.nvidia.com/transforming…

Learn how OneAngstrom and NVIDIA-powered generative AI can streamline your workflows and boost productivity bit.ly/49dpDEK

NVIDIA CEO: „W tym roku każda branża stanie się branżą technologiczną”. #AIHealthcare AI-accelerated drug design Szef spółki w rozmowie podczas konferencji health care #JPM24 starał się przedstawić nam, jak widzi przyszłość kombinacji medycyna PLUS technologia. „Teraz można rozpoznać i nauczyć się języka niemal wszystkiego, co ma strukturę i można go przetłumaczyć na wszystko, co ma strukturę — ​​a więc tekst-białko, białko-tekst. To jest rewolucja generatywnej sztucznej inteligencji. (...) Dzięki sztucznej inteligencji i przełomowej pracy, jaką wykonała nasza branża, w dramatyczny sposób zniwelowaliśmy przepaść technologiczną. (...) Każdy jest programistą, a język programowania przyszłości nazywa się „ludzki”.” Huang prześledził zaangażowanie firmy NVIDIA w "przyspieszoną opiekę zdrowotną" od dwóch projektów badawczych, które przykuły jego uwagę około 15 lat temu: jeden w Mass General wykorzystywał procesory graficzne NVIDIA do rekonstrukcji obrazów tomografii komputerowej, a drugi na Uniwersytecie Illinois Urbana-Champaign zastosował akcelerację GPU do dynamiki molekularnej. „To otwarło mi umysł, że możemy zastosować tę samą metodologię, której używamy przy projektowaniu chipów wspomaganych komputerowo, aby pomóc światu odkrywania leków przejść od odkrywania leków wspomaganego komputerowo do projektowania leków wspomaganego komputerowo” (...) Jeśli powiększymy to miliard razy, moglibyśmy symulować biologię”. Huang wyjaśnił, że po 40 latach postępu w projektowaniu chipów wspomaganych komputerowo inżynierowie mogą teraz budować złożone systemy obliczeniowe w całości w oparciu o symulację. W ciągu następnej dekady to samo może dotyczyć projektowania leków przyspieszanego przez sztuczną inteligencję. AI-accelerated drug design „Prawie wszystko w dużej mierze zacznie się w krzemie i w dużej mierze zakończy się w krzemie” ➡️ To co oprogramowania CAD (computer-aided design) oraz EDA (electronic design automation) zrobiły dla projektowania chipów, ekosystem CADD (computer-aided design and drafting) może też zrobić dla projektowania leków - to z poniedziałkowej prezentacji Kimberly Powell, VP obszaru Healthcare w #NVIDIA Powell ogłosiła, że ​​Recursion jest pierwszym partnerem hostingowym oferującym podstawowy model w postaci usługi chmurowej NVIDIA BioNeMo, która w tym miesiącu wchodzi w fazę beta. Ogłosiła również, że Amgen, jedna z pierwszych firm, które wykorzystały BioNeMo, planuje przyspieszyć odkrywanie leków dzięki generatywnej sztucznej inteligencji i NVIDIA DGX SuperPOD — oraz że BioNeMo jest wykorzystywane przez coraz większą liczbę firm biotechnologicznych, farmaceutycznych, dostawców oprogramowania AI i integratorów systemów. Wśród nich są: Deloitte, Innophore, Insilico Medicine, OneAngstrom, Recursion i Terray Therapeutics. ⬅️ Wracając do rozmowy z CEO: "plany Nvidia na rzecz przyspieszonej opieki zdrowotnej obejmują algorytmy do mikroskopii krioelektronowej, krystalografii rentgenowskiej, sekwencjonowania genów, przewidywania struktury aminokwasów i badań przesiewowych wirtualnych cząsteczek leków. W miarę rozwoju sztucznej inteligencji dostęp do tych narzędzi obliczeniowych staje się znacznie łatwiejszy." Oprócz opracowywania leków ta transformacja w kierunku przemysłu sterowanego oprogramowaniem i opartego na sztucznej inteligencji przyczyni się również do rozwoju instrumentów medycznych. „Instrument medyczny już nigdy nie będzie taki sam. Systemy ultradźwiękowe, systemy tomografii komputerowej, wszelkiego rodzaju instrumenty – zawsze będą to urządzenia plus cała gama sztucznej inteligencji” – powiedział Huang. „Wartość, która stworzy, i możliwości, które stworzysz, będą niesamowite”. Link do materiału, gdzie dostępne są także odniesienia do pełnego wywiadu oraz prezentacji K. Powell: blogs.nvidia.com/blog/nvidia…

💡 NVIDIA CEO Jensen Huang ヘルスケア了解における「生成AI革命」を予測 1️⃣ AIとヘルスケア産業の進化 NVIDIA ( $NVDA ）CEOのJensen Huangは、J.P. Morgan Healthcare Conferenceで「すべての産業がテクノロジー産業に変わる」と予測しました。彼は、AIが構造を持つあらゆるものの言語を認識し、それを他の構造に翻訳する能力を持っていると述べ、これを「生成AI革命」と呼んでいます。この進歩は、特にテキストとタンパク質間の変換に注目されています。 2️⃣ NVIDIAとヘルスケア業界のパートナーシップ NVIDIAのVP、Kimberly Powellは、BioNeMoクラウドサービスを通じて基礎モデルを提供し、Amgen（ $AMGN ）などの企業がこのプラットフォームを使用して薬物発見を進めていることを発表しました。さらに、Deloitte、Innophore、Insilico Medicine、OneAngstrom、Recursion( $RXRX )、Terray Therapeuticsなど、多くのテックバイオ企業や製薬会社、AIソフトウェアベンダー、システムインテグレーターがBioNeMoを活用しています。 3️⃣ NVIDIAの医療分野への影響 Huangは、医療分野へのNVIDIAの影響を強調し、特にマサチューセッツ総合病院でのCT画像の再構築とイリノイ大学アーバナ・シャンペーン校での分子動力学へのGPUアクセラレーション応用を例に挙げました。これらは、コンピュータ支援からAI加速へと進化する薬物設計の分野でのNVIDIAの重要な役割を示しています。 📍 まとめ Huangは、AIが医薬品開発と医療機器の進化に革命をもたらすと強調しました。クライオ電子顕微鏡、X線結晶構造解析、遺伝子配列解析、アミノ酸構造予測、仮想薬物分子スクリーニングなど、多岐にわたる分野でのアルゴリズムの開発が注目されています。これらの進展は、医療機器の進化を加速し、新たな価値と機会を生み出すことが期待されています。

OneAngstrom is integrating @NVIDIA #BioNeMo cloud APIs into the #SAMSON platform to make advanced molecular design more accessible than ever before. #JPM24 #GenerativeAI #DrugDiscovery @NVIDIAHealth @jpmorgan linkedin.com/pulse/transform…

🌟 Open PhD Candidate position at OneAngstrom 🌟 We are thrilled to share that, as a member of the PhotoCaM Marie Skłodowska-Curie Actions Doctoral Network, OneAngstrom is seeking a highly motivated individual with a strong background in computer science. 🚀 Key Responsibilities: Develop and implement innovative computational methods for accurate pKa prediction. Collaborate with our European partners, contributing to a rich, international research environment. Prerequisites: - Master’s degree in Computer Science or a related field. - Demonstrated expertise in computational methods, algorithms, and programming. - Strong analytical and problem-solving skills. - Excellent communication and teamwork abilities. Unique Opportunity: Be a part of an EU-funded international network, gaining unparalleled exposure. Travel across Europe to collaborate with our network partners, enriching your research experience and cultural understanding. If you have a strong computational background and a drive to innovate, we would love to hear from you! 📩 How to apply: Contact us through here or send a mail to photocam-phd@oneangstrom.com About PhotoCaM: Photosynthesis relies on harvesting the sun light and on transforming the solar energy into chemical energy to sustain almost all life on earth. An enhanced molecular-level understanding of photosynthesis and particularly of the light-harvesting process is of key significance. In this Doctoral Network we aim at training a new generation of computational scientists which can treat complex and interdisciplinary problems such as light harvesting on a molecular level using theoretical and computational tools. The interdisciplinary nature of the problem requires a combined knowledge from biology, chemistry, physics and computer science in order to combine state-of-the-art approaches like molecular dynamics simulations, quantum chemistry, theoretical spectroscopy and machine learning into multi-scale schemes. This joint undertaking is a unique chance in research but especially also in training young scientists in interdisciplinary teamwork, method training and high-performance computing in academic as well as non-academic settings. constructor.university/resea… Network Partners: Constructor University, Bremen, Germany University of Patras, Greece University of Pisa, Italy University of Groningen, Netherlands Vilnius University, Lithuania ICFO – Institute of Photonic Sciences, Castelldefels, Spain Johannes Kepler University Linz, Austria Karlsruhe Institute of Technology, Germany Faccts GmbH, Cologne, Germany OneAngstrom SAS, Grenoble, France #OneAngstrom #phdposition #ComputationalResearch #EUResearch #CareerOpportunity

🌟 Exciting News! We are thrilled to announce that OneAngstrom has been collaborating with @nvidia to integrate BioNeMo Generative AI services into the #SAMSON molecular design platform! The first batch of services is now available as a beta to all users. 💡 What's new? NVIDIA BioNeMo Protein Folding Services, including AlphaFold 2, ESMFold, and OpenFold, are now seamlessly integrated into SAMSON. The services are usable in just a few clicks. 🚀 What does this mean? You can now enjoy greater productivity thanks to streamlined workflows and expanded functionality by combining BioNeMo folding services to other SAMSON extensions for modeling, simulation, analysis, visualization, scripting, etc. ✨ But wait, there's more! Of course we're not stopping here! More BioNeMo services are coming to SAMSON, including for molecular docking, molecule generation, and protein generation. I want to warmly thank @nvidia, and in particular David Ruau @druau and Kimberly Powell @kpowgerade, for their continued trust. OneAngstrom is excited to bring exceptional AI services to more modelers through the SAMSON platform, and we are looking forward to continuing our journey together. This collaboration represents a significant step forward in democratizing access to state-of-the-art AI technologies for scientists and researchers worldwide. #NVIDIA #OneAngstrom #BioNeMo #SAMSON #GenerativeAI #ProteinFolding #Innovation

OneAngstrom Update! SAMSON 2023 R1 🧠⚛️ SAMSON AI: An intelligent assistant that executes commands! Molecular Cycles: studio-quality images & animation. Integrated Python Dev Environment: embed Python scripts, research papers, & ML apps. documentation.samson-connect… @StephaneRedon

I think you might like #Samson from OneAngstrom

The SAMSON team at OneAngstrom wishes you a happy holiday!

【動画紹介】 当社YouTubeチャンネルにてSAMSON connect (OneAngstrom社)を使用したタンパク質のモデリングの動画をアップロード！ モデリングの他、リガンドドッキングや分子動力学シミュレーションにも対応！ 動画リンク： youtube.com/watch?v=reRD38RT… #分子モデリング　#分子動力学　#フィルジェン