Structural biology is facing a critical limitation: most atomic structures are determined from isolated, purified proteins frozen in artificial states.
#Nobelist Kurt Wüthrich outlined the roadmap to break this boundary by shifting structural biology in vivo – directly inside living cells and higher organisms.
While current cryo-electron tomography offers low resolution, Wüthrich championed the untapped potential of combining Nuclear Magnetic Resonance (NMR) spectroscopy with Magnetic Resonance Imaging (MRI), fusing high-resolution molecular interaction data with precise geographic anatomical mapping.
Watch his full keynote speech: youtube.com/watch?v=7tVffwkH…
#StructuralBiology #Biology #WLS #WLS26 #Science #BasicScience #Dubai #UAE
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