This AI-powered microscope doesn’t just observe cells—it thinks, learns, and designs its own experiments. See how it’s helping scientists uncover new paths to treating Parkinson’s disease and other neurodegenerative disorders. youtube.com/watch?v=QprT47kR…

In our latest newsletter, learn how the brain clears away its own cellular waste, discover how this microscope runs its own experiments, and meet Kevin Pastores, whose work in the Flow Cytometry Core leads him to collaborate all across the organization. mailchi.mp/gladstone/cell-si…

🚨 NEW PUBLICATION 🚨 "A focal ischemic stroke of the somatosensory thalamus produces persistent spontaneous pain–like behavio" from the lab of Jeanne Paz. sciencedirect.com/science/ar…

Nearly 20 years after his landmark study uncovered novel roles of tau in Alzheimer’s disease, Gladstone’s Lennart Mucke shares his perspective on new clinical data that could transform the future of brain health. bit.ly/4yj02rl

We're partnering with @claudeai for a global virtual hackathon exploring how AI can accelerate biomedical discovery. Work with datasets from Gladstone scientists, build with Claude Science, and compete for $100k in Claude API and usage credits. ➡️ bit.ly/4ePGFwY

We’re working with @AnthropicAI and @GladstoneInst to produce Built with Claude: Life Sciences. Join to build for one week with the Anthropic Gladstone team, get insights into Claude Science & Claude Code, and demo for the team behind it. Compete to win $100k in Claude API credits 🏆 And it’s ALL online, accessible wherever in the world you are 🌎 Apply below 👇

We're so excited about this partnership! Learn how to apply for the hackathon 👉cerebralvalley.ai/e/built-wi…

This year’s Pew scholars will explore cutting-edge research at the forefront of cancer biology, neuroscience, infectious disease prevention, and more. We’re thrilled that our own Magnus Hoffmann is among the 36 researchers recognized by @pewtrusts. bit.ly/43ERsoE

Read more about this work: gladstone.org/news/how-ai-pi…

"By creating a platform that allows us to decode the language of life as it’s written in DNA, we will ultimately be able to predict disease before it happens and intervene."

Finally, the scientists use all the data from the experiments to retrain the AI model, telling it which predictions were right and which were wrong, to make it better, faster, and more accurate—and start the whole process again.

Then, the edited cells are analyzed using a new measurement technology developed by Vijay Ramani. His team can confirm the edit each cell received and determine how that edit affected the cell’s function.

The AI predictions are then tested in @seth_shipman's lab. His group invented a new method to edit the DNA of thousands of human cells—all at once.

The first component is an AI model, designed by Katie Pollard’s team, that can look at millions of genome sequences and predict which DNA changes are most likely causing disease.

They’ve built a platform that combines advanced computational models with novel tools in the experimental lab to test their hypotheses about how DNA works.

Gladstone scientists who develop new technologies— both AI models on the computer and molecular tools in the lab—are coming together to solve one of the most challenging problems in science.

How are Gladstone researchers utilizing AI in the lab? 🧵

A genome-scale CRISPRi perturbation atlas of human induced pluripotent stem cells nature.com/articles/s41587-0…

#PittMed, alongside @Stanford University and @GladstoneInst, has been awarded a new center to help turn phage therapy into a reliable treatment for antibiotic-resistant ESKAPE infections. Discover how they’re closing key gaps in the field at tinyurl.com/2jbwz5xn.

Great science is a team effort. Kevin Pastores shares how Gladstone's Flow Cytometry Core works with researchers across the organization—from designing experiments and training scientists to analyzing data and partnering with other core facilities.

Do you know someone who should be honored for their work in stem cell biology or regenerative medicine? The deadline to nominate them for the Ogawa-Yamanaka Stem Cell Prize is approaching. Learn more: gladstone.org/ogawa-yamanaka… @CellPressNews @CellStemCell