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Coefficient Giving @coeff_giving

Coefficient Giving's mission is to help others as much as we can with the resources available to us.

Joined May 2014
  • Posts 893
  • Following 233
  • Followers 20,632
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Coefficient Giving
 @coeff_giving
18 Nov 2025
1/4 Over the last few years, we’ve grown from working primarily with a single foundation to partnering with more philanthropists who share our commitment to high-impact giving. To better reflect this, Open Philanthropy is becoming Coefficient Giving.
Alexander Berger
 @albrgr
18 Nov 2025
Some news: Open Philanthropy is now Coefficient Giving! Our mission is unchanged but the new name reflects our growing work with other donors to multiply the impact of their giving. 🧵 on our work to make philanthropy a more efficient "market" and plans going forward:
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Most nonprofits start with a founder who cares about a cause. Ambitious Impact (@Charity_Ep) works backwards: its staff research the most cost-effective interventions, then recruit entrepreneurs to launch dedicated organizations.
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Through eight years of cohorts, @Charity_Ep has helped to launch some incredible nonprofits — including @LeadElimination, working to prevent lead poisoning across 40 countries, and Ansh, which works on improving preemie care in India.
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We spoke with @Charity_Ep's CEO, Samantha Kagel, about the org’s approach to nonprofit entrepreneurship as well as some of her favorite incubatees. Full Q&A here: coefficientgiving.org/resear…
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Coefficient Giving reposted
Global Health NOW @ghn_news
Jun 30
Strep A—the bacterium behind strep throat and impetigo—kills hundreds of thousands of people a year, mostly young people in LMICs—yet Strep A vaccine R&D is chronically underfunded, writes @Kat_a_Collins of @coeff_giving. globalhealthnow.org/2026-06/…

A Vaccine for Strep A May Finally Be in Reach

Strep A—the bacterium behind strep throat and impetigo—kills hundreds of thousands of people a year, mostly young people in LMICs—yet Strep A vaccine R&D is chronically underfunded.

globalhealthnow.org
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AI is advancing fast, with profound implications for human health and wellbeing. We're launching a $10-30M RFP for work to help ensure AI improves human health and wellbeing, with particular attention to risks for and benefits to the global poor. 🧵
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This RFP is distinct from our Navigating Transformative AI fund, which focuses on catastrophic risk. It’s also distinct from “AI for good” interventions — projects where AI is directly used as a tool to improve health, education, agriculture, etc.
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Grants range from under $100k to $10m, and are open to individuals, institutions, think tanks, nonprofits, and for-profits globally. Apply by August 21: fillout.coefficientgiving.or… Full RFP: coefficientgiving.org/funds/…

Coefficient Giving Expression of Interest

Apply to our open call here.

fillout.coefficientgiving.org
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While our global health work has historically not been closely tied to advances in AI, this RFP assumes AI could produce discontinuous change, shifting where the bottlenecks to improving lives currently are.
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We're launching a $10 million RFP for R&D on one of the biggest barriers to alternative protein adoption: taste. 🧵
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We're looking for researchers and teams from outside the usual alt-protein circles, including chemists, food physicists, plant breeders, formulators, and engineers. Applications from universities, research institutes, startups, companies, and nonprofits are all welcome.
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Awards range from $100k to $1m, with typical durations of 2-3 years. Learn more and apply here by August 10: bit.ly/cgaprfp
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Our CEO @albrgr joined @AlterIgoe on @Devex's Theory of Change podcast to discuss where philanthropic effort can have the biggest impact, and why structural gaps in markets and governments leave so many important problems chronically underfunded.
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Read/watch the full episode: Spotify: open.spotify.com/episode/35i… Apple Podcasts: podcasts.apple.com/us/podcas… YouTube: youtu.be/0SLzoKxQqHg

How Alexander Berger weighs the world’s biggest problems

Theory of Change · Episode

open.spotify.com
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Saad Bhamla is a leading figure in the “frugal innovation” movement, dedicated to building cheap versions of scientific tools for low-resource settings. His latest project might be his most ambitious yet: a portable device to detect TB and other diseases for less than $100. 🧵
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Our Science team saw an opportunity to connect two grantees of ours working in parallel: Bhamla with the engineering background to build a cheap Raman device, and Thai researchers Kiatichai Faksri and Noppadon Nuntawong with the TB expertise and samples to test it.
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We spoke with both teams about frugal innovation what a cheap, reliable TB test could mean for low-resource settings: coefficientgiving.org/resear…
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