What if one of cancer’s most devastating side effects could be reversed?
Cancer cachexia is a debilitating wasting syndrome that affects many people with cancer, yet treatment options remain limited.
Team CANCAN has published new research in
@ScienceMagazine that highlights a previously underappreciated driver of cancer cachexia: localised signals from tumours acting directly on sensory neurons.
This is a big step toward reframing cancer cachexia as not only a systemic metabolic condition, but also one shaped by tumour–nerve communication.
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@ThalesPapaG, Co-Investigator on team CANCAN and team InteroCANCEption, explains the discovery and what it could mean for patients.
Read the full paper:
science.org/doi/10.1126/scie…
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Team CANCAN is funded by
@CR_UK and
@theNCI through Cancer Grand Challenges.